While Andy Murray had to endure a five-setter against Czech Radek Stepanek to enter the men's singles second round, German Angelique Kerber failed to move past Dutch Kiki Bertens.
Raonic fired 18 aces to beat top seed Tomas Berdych 7-6 (7/4), 6-3 in the final.
Top-seeded Tomas Berdych defeated Gilles Simon of France 6-7 (5), 6-2, 7-5 in nearly three hours while Raonic ousted defending champion Richard Gasquet 3-6, 7-5, 6-4.
Leander Paes and his new partner Daniele Bracciali went down to Jamie Murray and John Peers 6-3 6-4 in the last-four clash in the Thailand Open in Bangkok.
Berdych beat Yen-hsun Lu of Taiwan 7-6 (7), 6-4 to maintain his record of never losing before the semifinals in Thailand while Simon emerged 6-4, 5-7, 6-4 winner over Igor Sisjling.
Simon, who flew to Asia immediately after defeating compatriot Jo-Wilfried Tsonga to win the Metz title at the weekend, admitted that he did not know that he was on the cusp of a personal milestone.
The Indo-Sweden pair of Bhupathi and Lindstedt lost 6-2 3-6 8-10 to Daniel Gimeno-Traver of Spain and Paolo Lorenzi of Italy in just 59 minutes.
Richard Gasquet snapped a title drought stretching back two-and-a-half years as he beat close friend Gilles Simon 6-2, 6-1 in an all-French final on Sunday at the Thailand Open.
Gilles Simon upset top-seeded Janko Tipsarevic 6-4, 6-4 on Saturday to set up an all-French final against Richard Gasquet at the Thailand Open.
2009 Thailand Open winner Gilles Simon of France continued to struggle with shoulder problems but managed a 6-4, 6-4 defeat of Japan's Go Soeda on Thursday to reach the quarter-finals.
Gael Monfils made back-to-back quarterfinals by ousting sixth-seeded Victor Troicki of Serbia 7-5 7-5 in the second round of the Thailand Open on Thursday.
France's Gael Monfils said he was targeting a return to the top 10 Wednesday as he continued his strong return from injury with a 6-4, 2-6, 7-5 over Kevin Anderson in the Thailand Open's first round.
Philipp Petzschner advanced to the second round of the Thailand Open by beating Peerakiat Siriluethaiwattana of Thailand 6-1, 6-2 on Monday.
Fourth-ranked Andy Murray claimed his 19th career title in beating American Donald Young 6-2, 6-0 in the final of the Thailand Open at the Impact Arena in Muang Thong Thani on Sunday.
Andy Murray will have the experience edge when the top seed faces untested Donald Young in Sunday's final of the ATP Thailand Open.
Andy Murray was a step closer on Friday to his goal of finishing the season world number three as he beat promising Bulgarian teen Grigor Dimitrov 6-4, 6-4 to reach the last four at the Thailand Open.
France's Gael Monfils, returning to tennis after an injury layoff, reached the semi-finals of the ATP Thailand Open on Friday with a 7-5, 7-6 (7/4) win over Jarkko Nieminen.
Andy Murray made a winning return to the Thailand Open Thursday to reach the last eight and later played down talk of a player strike as questions over the ATP calendar resurfaced.