Devastated former Olympic champion Carolina Marin withdrew in tears from her badminton semi-final on Sunday after her right knee buckled in distressing scenes.
This is Sindhu's sixth loss on the trot against her arch-rival, dating back to 2018.
PV Sindhu blew away an 18-15 lead in the decider to go down to familiar foe Carolina Marin in a thrilling three-game women's singles pre-quarterfinal clash at the Singapore Open on Thursday.
World number 12 PV Sindhu and Carolina Marin, currently ranked sixth, had earlier talked about good camaraderie between them but they showed none of it on the court on Saturday.
Sixth seed Sindhu, who was playing her first match since she sustained a stress fracture on her left ankle en route her Commonwealth Games gold in August, lost 12-21, 10-21, 15-21 to Rio Olympics champion Carolina Marin of Spain in 59 minutes.
Lakshay Sen and HS Prannoy, have been drawn to clash in the pre-quarterfinals of the Indonesia Open
PV Sindhu will look to be at her best on the big stage when she begins her title defence at the BWF World Championships beginning in Spain on Sunday.
Carolina Marin had withdrawn from the All England Championships this year after suffering the injury during the Swiss Open. The 28-year-old had announced her plans of making a comeback at the home World Championships beginning in Huelva, Spain.
PV Sindhu, the world number seven, has seen a resurgence in form as she had reached semifinals in the last three tournaments she had played.
Tokyo Games: PV Sindhu passed on her best wishes to Carolina Marin, who will miss the Olympics due to an ACL injury.