Shanghai:
Del Potro had 27 winners and only eight unforced errors in a 6-3, 6-3 win over Spain's Nicolas Almagro.
Tsonga beat Germany's Florian Mayer 6-2, 6-3.
Del Potro, who moved back into the top five in the rankings this week, can clinch a berth in next month's year-end championships in London by reaching the final.
Tsonga is further back after missing several months with a knee injury, but he moved into the eighth and final qualifying spot with his win on Friday, just ahead of French compatriot Richard Gasquet.
Topics mentioned in this article
Tennis
Juan Martin del Potro
Samantha Stosur
Roger Federer
Novak Djokovic
Gael Monfils
Rafael Nadal
Wimbledon 2011
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