David Warner will be back in action for SunRisers Hyderabad.
India A won the third and final match by a convincing 75-run margin.
Manish Pandey's unbeaten 111-run knock propelled India A to a five-wicket win. India A now have an unassailable lead of 2-0 in the three-match series.
The first T20I in Brisbane may provide Rohit Sharma a chance to create history.
Rishabh Pant is in line to make his ODI debut with India announce the XII for the first match against the Windies on Sunday.
Manish Pandey took a spectacular catch at the long-on boundary to send Pakistan captain Sarfraz Ahmed packing.
Virat Kohli will be under pressure to meet all India's engagements over the next few months.
The India B team will be led by Manish Pandey.
India are scheduled to play two T20Is against Ireland and three T20Is, three ODIs and five Tests against England.
Money does not necessarily beget performance, as the Indian Premier League (IPL) 2018 amply displays.
The absence of David Warner leaves a yawning gap in the SunRisers Hyderabad batting and Manish Pandey would be keen to plug that.
Needing five off the final delivery, Karthik smashed Soumya Sarkar over extra-cover as a second-string Indian side held its nerve in a tense situation to chase down a target of 167 in 20 overs.
A clinical India defeated Sri Lanka comprehensively by six wickets to continue their their winning run in the Nidahas Twenty20 Tri-Series on Wednesday.
Manish Pandey believes India will come back stronger in the virtual final at Newlands in Cape Town.
MS Dhoni looked visibly upset with his partner Manish Pandey and was also seen shouting at him angrily just before the second ball of the final over was about to be bowled.
Manish Pandey scored a fine 79 not out off 48 balls in the second T20 International against South Africa.
Captain JP Duminy and Heinrich Klaasen scored quick-fire half-centuries as South Africa beat India by six wickets in the second Twenty20 International at the SuperSport Park in Centurion on Wednesday.