Chelsea's lacklustre FA Cup fifth round exit was another painful blow for Maurizio Sarri, who is facing a fight to save his job following a dismal debut season.
Manchester United face Fulham in the Premier League, which will be followed by a mouthwatering clash against PSG in the Champions League.
Ander Herrera scored the second goal for Manchester United against Cardiff City.
Herrera joined Manchester United from Athletic Bilbao in 2014 and his current contract is set to expire in the summer of 2019.
Jose Mourinho was finally given something to smile about as a tempestuous trip to the United States ended with a 2-1 victory over former club Real Madrid thanks to first-half strikes from Alexis Sanchez and Ander Herrera.
Goals from Alexis Sanchez and Ander Herrera cancelled out Dele Alli's opener and ensured that Tottenham's decade-long wait for a trophy continues.
Manchester United took the lead when Ashley Young crossed for Ander Herrera to volley home, but Arsene Wenger's side earned a point in the 82nd minute when Theo Walcott's shot nicked off Blackett and looped over United substitute goalkeeper Victor Valdes.
Manchester United F.C. sank Aston Villa 3-1, thanks to a brace from Herrera and a thunder strike for Rooney, to soar above Manchester City.
Manchester United midfielder Ander Herrera alleged to be involved in a possible match-fixing claim. Herrera played for Spanish side Real Zaragoza in the match in question on May 21, 2011.