Arsenal midfielder Eberechi Eze tormented Tottenham again as his double revived the Premier League leaders' title bid in a 4-1 rout of their north London rivals.
After Real Madrid fell to a 2-1 defeat at Osasuna on Saturday, Hansi Flick's side moved a point clear of their bitter rivals with a comfortable victory at Camp Nou against the team in 19th.
Vinicius Junior was back on the score sheet for Real Madrid on Saturday, but the Brazilian was not able to prevent the Spanish league leader from falling to a surprise 2-1 loss to Osasuna.
The speedy left back covered his face with his jersey as he left the field early in the second half, raising fears over the extent of the injury just under four months before his country co-hosts the World Cup.
French league leader Lens was stunned by three second-half goals as Monaco came from behind to win 3-2 to give Paris Saint-Germain the chance to go top on Saturday.
Substitutes Henrikh Mkhitaryan and Manuel Akanji scored late for Inter Milan to stretch its Serie A lead to 10 points with an unspectacular 2-0 win at Lecce on Saturday.
Vitor Pereira made an impact in his first game in charge, leading Nottingham Forest to a 3-0 victory at Fenerbahce in the first leg of their Europa League playoff on Thursday.
Arsenal's Premier League title challenge suffered a major blow as they squandered a two-goal lead and conceded a stoppage-time equaliser in a damaging 2-2 draw at rock-bottom Wolves.
Norway's Bodo/Glimt stunned Inter Milan in the Champions League on Wednesday, beating last season's runners-up 3-1 in the first leg of their knockout phase play-off tie.
Benfica player Gianluca Prestianni has denied racially insulting Real Madrid forward Vinicius Junior during a Champions League match when he covered his mouth with his jersey.
Vinicius Junior scored and then alleged he had been racially abused during Real Madrid's 1-0 win away to Benfica in the first leg of their Champions League play-off tie on Tuesday, while Paris Saint-Germain came from two goals down to beat Monaco 3-2.
Madrid defender Trent Alexander-Arnold called the incident "a disgrace to football" while Benfica manager Jose Mourinho said Vincius had incited his players and fans by the way he celebrated his goal in the 1-0 win for Madrid.