While it was a cruise into the fourth round for both Rafael Nadal and Roger Federer, in the women's section Svetlana Kuznetsova, Caroline Wozniacki and Petra Kvitova were knocked from the US Open 2013 tournament. (All AFP images)
Nadal beat Ivan Dodig 6-4, 6-3, 6-3, affirming his favoritism to win this tournament. The second-seeded Spaniard has lost just 21 games across three matches and has faced only five break points, saving each one of them.
Federer then emerged on Arthur Ashe Stadium and notched an even more imperious victory, dominating Frenchman Adrian Mannarino in a 6-3, 6-0, 6-2 victory that came in just 81 minutes.
The 38th-ranked Dodig beat Nadal at the hard-court tournament in Montreal two years ago. But Nadal is looking like the king of hard courts these days, with an 18-match winning streak on the surface.
"I am winning because I am playing well from the baseline and I am making the right decisions in the right moments," Nadal said.
Fourth-seeded David Ferrer needed nearly three hours to down 172nd-ranked qualifier Mikhail Kukushkin 6-4, 6-3, 4-6, 6-4. His next opponent is No. 18-seeded Janko Tipsarevic, who also took four sets to knock off 20-year-old American Jack Sock 3-6, 7-6 (1), 6-1, 6-2.
Eighth-seeded Richard Gasquet and No. 10 Milos Raonic set up another fourth-round matchup with victories.
The losses by Isner and Sock meant wild card Tim Smyczek was the only American man left in the singles draw.
In the women's draw, second-seeded Victoria Azarenka took 2 hours, 40 minutes to close out Alize Cornet 6-7 (2), 6-3, 6-2.
13th-seeded Ana Ivanovic, beat young American Christina McHale 4-6, 7-5, 6-4 victory in 2 hours, 26 minutes. McHale served for the match at 5-4 in the second set and had two break points at 5-5.
While McHale lost, another young American Alison Riske pulled off an impressive scalp by cruising past former Wimbledon champion Petra Kvitova 6-3, 6-0. The Czech had been in bed with a fever the day before.
No. 10 Roberta Vinci will face unseeded Camila Giorgi (in pic) in an all-Italian match. The 136th-ranked Giorgi defeated 2009 U.S. Open runner-up Caroline Wozniacki, who was seeded sixth, 4-6, 6-4, 6-3.