Top seed Novak Djokovic survived a first-set wobble to reach the US Open third round Friday but Wimbledon runner-up Sabine Lisicki once again flopped when removed from her London grasscourt comfort zone. (All AFP images)
World number one Djokovic won 12 of the last 14 games to defeat Germany's Benjamin Becker 7-6 (7/2), 6-2, 6-2 after saving two set points in the 10th game of the opening set.
Russian 24th seed Makarova clinched a 6-4, 7-5 win over German 16th seed Lisicki, who had wowed Wimbledon last month when she defeated Serena Williams on her way to a final loss against Marion Bartoli.
In the women's event, Chinese fifth seed Li Na and third-seeded Pole Agnieszka Radwanska made the last 16.
Li hit 11 aces in a 6-2, 7-5 victory against teenager Laura Robson, avenging her loss to the Briton at the same stage last year. Radwanska beat Russian Anastasia Pavlyuchenkova 6-4, 7-6 (7/1).
British third seed Andy Murray, the reigning Wimbledon and Olympic champion, advanced with a 7-5, 6-1, 3-6, 6-1 victory over Argentina's 81st-ranked Leonardo Mayer in a match of rivals who were both born on May 15, 1987.
Lleyton Hewitt, the 2001 champion, knocked Argentine sixth seed and 2009 winner Juan Martin Del Potro out of the US Open on Friday in a stunning five-set upset.
Hewitt, 32 years old and down at 66 in the rankings after a lengthy battle with injuries, won 6-4, 5-7, 3-6, 7-6 (7/2), 6-1 in a trademark warrior-like performance that recalled his golden days when the Australian was number one in the world and collected the Wimbledon title.
Japanese qualifier Kurumi Nara, who had never before reached the third round in any tour-level event, saw her US Open run ended Friday with a 6-4, 7-6 (7/5) loss to Serbian ninth seed Jelena Jankovic.
Nara's only prior Grand Slam appearances were a 2010 second-round Wimbledon effort and a first-match loss at the 2010 French Open.
Jankovic and Nara exchanged early service breaks in the match but the Serbian star broke her at love in the final game of the first set.
Former world number one Martina Hingis had her Grand Slam comeback after six years of retirement cut short on Friday with two doubles defeats.
Hingis and Slovakian partner Daniela Hantuchova lost to Italian top-seeded defending champions Sara Errani and Roberta Vinci 6-3, 7-5 in women's doubles, with Hingis double faulting away the final points.
In a later match, Sweden's Robert Lindstedt and Taiwan's Chan Yung-Jan beat wildcard entrants Hingis and India's Mahesh Bhupathi 7-6 (7/5), 7-6 (7/5) in mixed doubles.