New York :Home hopes in the US Open were blown away by Switzerland's Stanislas Wawrinka on Thursday when he outlasted Sam Querrey in a marathon fourth round tie.
The 7-6 (11/9), 6-7 (5/7), 7-5, 4-6, 6-4 defeat means that there will be no US player in the men's singles quarter-finals for the second year in a row.
Last year was the first time that had happened in the Open era dating back to 1968.
The 20th-seeded Wawrinka joins Roger Federer in the last eight, making it the first time two Swiss players have reached the quarter-finals of a Grand Slam in the Open era.
The match, played in tough, windy conditions, lasted four hours 28 minutes.
"I think for sure the crowd was hoping that he can stay in the tournament. But if you watch the match they were very fair. For me it was great to play that kind of match with that crowd," the 25-year-old Wawrinka said after reaching his first Grand Slam quarter-final.
His opponent for a place in the semi-finals will be 12th-seeded Russian Mikhail Youzhny, who defeated Tommy Robredo of Spain 7-5, 6-2, 4-6, 6-4.
The 22-year-old Querrey, also seeking to reach his first Grand Slam quarter-final, said that the difference between winning and losing had been slight.
"Just a couple of points here and there, It was like every set was like that. Just really a couple of points in every set that made the difference," he said.
Wawrinka reached the fourth round by playing some of the best tennis of his life to defeat fourth seed Andy Murray of Britain in four sets, while all the pressure was on Querrey as the last US player left in the tournament.
The Swiss player let slip a golden chance of clamping a stranglehold on the match when he squandered four second set points before Querrey run off six points in a row from 0-3 down in the ensuing tie-break to level the match.
After sharing the third and fourth sets, both players looked leg weary going into the fifth set and another tie-break looked on the cards until Wawrinka gathered his forces for one last push in the 10th game.
He finally finished Querrey off with a chip and charge on his second match point.
The 28-year-old Youzhny, the sole surviving Russian in the men's draw, grabbed the first break of serve of the match in the 11th game to take the first set against Robredo.
He then had back-to-back breaks in the second to take a commanding two sets to love lead.
Games went with serve in the third set until 5-4 for Robredo when the Spaniard finally bagged a break of serve, Youzhny hitting a forehand wide on break point.
Robredo was looking the stronger going into the fourth set but it was Youzhny that made the breakthrough in the fifth game.
He set up break point with a deft backhand sliced drop shot and then cashed in when his service return clipped the net and dropped stone dead on Robredo's side.
From 3-2 up, the Russian held serve three times to advance to the last eight.
It is the second time that Youzhny has made it through to the last eight in New York following his run into the semi-finals in 2006 when he beat Rafael Nadal along the way.
"I like the result and actually I like how I played today," Youzhny said.
"Of course, I have some mistakes and I was a little bit lucky in the fourth set."
Robredo was one of five Spaniards in action in the four games comprising the top half of the draw in the fourth round.
The other four were paired in the first quarter with top seed Rafael Nadal taking on 23rd seed Feliciano Lopez and eighth seed Fernando Verdasco going up against 10th seed David Ferrer later Tuesday.