Uruguay named fit-again striker Luis Suarez in the starting line-up to face England on Thursday as they try to get their World Cup campaign back on track.
Liverpool's Suarez, last season's Premier League top-scorer, will partner Paris Saint-Germain's Edinson Cavani up front after recovering from knee surgery last month.
Diego Godin got the nod as captain after regular skipper and fellow defender Diego Lugano was ruled out with a knee problem.
Both Uruguay and England lost their opening Group D games, meaning Thursday's clash in Sao Paulo could be pivotal to their chances.
England will name their team closer to the match's 12:30 am IST kick-off.
Fernando Muslera; Martin Caceres, Jose Maria Gimenez, Diego Godin (captain), Alvaro Pereira; Alvaro Gonzalez, Egidio Arevalo Rios, Nicolas Lodeiro, Cristian Rodriguez; Edinson Cavani, Luis Suarez